Prednisone or Prednisolone?

February 6, 2023

Prednisone and prednisolone are glucocorticoids (or corticosteroids), similar to hormones produced by the human body in the adrenal glands, which sits atop the human kidneys. They generally prescribed to suppress inflammation or an overactive immune system in the body. The practical difference between the two drugs is that prednisone must be converted to prednisolone in the liver before it can go to work. For this reason, prednisolone is usually prescribed for patients with liver disease. 

The list of inflammatory conditions treated with prednisone or prednisolone is long: 

  • Psoriasis
  • Arthritis
  • Allergies
  • Certain cancers
  • Breathing problems caused by inflammation
  • Eye inflammation
  • Immune system disorders
  • Certain blood disorders 

The list of side effects includes:

  • Insomnia
  • Headache
  • Dizziness
  • Inappropriate happiness or mood swings
  • Personality changes
  • Bulging eyes
  • Fragile, thin skin
  • Easy bruising
  • Inappropriate hair growth
  • Acne
  • Increased waist size or fat on upper back
  • Fatigue
  • Weakness
  • Scanty or absent menstrual periods
  • Poor sexual desire
  • Heartburn
  • Increased sweating

Cost of prednisone and prednisolone?

The price of prednisone ranges from $2.00 to $10.00 for a bottle of 10 tablets, strength 20mg. The price of prednisolone ranges from $8.00 to $19.00 for a bottle of 30ml, strength 15mg/5ml. To find the least expensive pharmacy near you, and to get a coupon, click here.

Where can I get prednisone and prednisolone from?

These medications need to be prescribed to you by a licensed physician or prescriber. QuickMD can prescribe these corticosteroids to you, if medically necessary and appropriate. 

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