What is microdosing of Suboxone (buprenorphine)?

December 20, 2022

What is meant by microdosing of Suboxone? The main medication in Suboxone is buprenorphine, given to treat opiate use disorder. It works by fitting into opiate receptors, tiny structures in the brain and throughout the body. When buprenorphine is in the opiate receptors, opiates such as heroin and fentanyl cannot reach the receptors easily, and euphoria, or a “high”, cannot be achieved. This helps patients lose their craving for opiates and stop using them.

When Suboxone is taken while the problematic drug is still in the system, the buprenorphine will replace the drug of abuse, which is what it is supposed to do. This can lead to withdrawal symptoms. For this reason, unless patients can wait enough time for the drug of abuse to leave their systems entirely, Suboxone can be given in microdoses frequently. This can limit symptoms of withdrawal. Discuss with your physician whether waiting for a standard dose or microdosing might be the better option for you.