What is the difference between Zubsolv and Suboxone? Both are brand names for medications that are composed of buprenorphine and naloxone, and both are used to treat opiate use disorder (OUD) as part of medication-assisted treatment (MAT) or teleMAT (MAT through telemedicine).
The main difference is in dosage, because Zubsolv has a higher absorption rate. The following table shows equivalent doses of Zubsolv and Suboxone.
| Zubsolv (buprenorphine/naloxone) | Suboxone (buprenorphine/naloxone) |
| 1.4mg/0.36mg | 2mg/0.5mg |
| 2.9mg/0.71mg | 4mg/1.0mg |
| 5.7mg/1.4mg | 8mg/2mg |
| 8.5mg/2.1mg | 12mg/3mg |
| 11.4mg/2.9mg | 16mg/4mg |
The most common dose is 8 mg of Suboxone, which is equivalent to 5.7 mg of Zubsolv. The other difference is in the available forms of the medicatios. Patients taking Suboxone have their choice of either tablet form or film. Either tablet or film is held under the tongue or against the cheek for a few minutes until dissolved. Zubsolv is available only in tablet form.
Is Zubsolv more expensive than Suboxone?
While Zubsolv tends to be more expensive than Suboxone (which is also available as generic medication), some insurances only cover Zubsolv. It is advisable to talk to your insurance to see which medication is covered.
Where can I get Zubsolv?
QuickMD is the largest MAT service in the United States. QuickMD doctors can prescribe both Zubsolv and Suboxone via telemedicine.