Plavix (clopidogrel) and aspirin (acetylsalicylic acid) both work to prevent blood clots by inhibiting a process called platelet clumping, which is when platelets stick together. These medications are vital in preventing clots that can block blood flow to the heart muscle (causing a heart attack) or brain tissue (causing a stroke). Various studies have determined the best usage scenarios for each medication.
When Should You Use Clopidogrel, Aspirin, or Both?
Here’s when you should use clopidogrel with or without aspirin for the following conditions:
- Stent Placement
- A stent is a wire mesh device placed into arteries to hold them open and can frequently produce clots. For a month to a year after the stent is installed, Plavix is given to prevent platelet clumping. This extended use of Plavix is necessary to ensure that the stent remains unobstructed and blood flow is maintained.
- Serious Chest Pain
- Serious chest pain can be caused by blockage in the coronary arteries, which feed oxygen-laden blood to the heart muscle. Plavix and aspirin are given during heart attacks or what is known as unstable angina (uncontrolled chest pain due to blockage of the coronary arteries). Plavix is continued for 9 to 12 months after a heart attack for prevention.
- Stroke
- A stroke, or cerebrovascular accident, can be caused by blockages in arteries feeding blood to the brain. After a stroke, either aspirin or Plavix lowers the risk of another stroke, but both drugs do not work better than either one alone and can increase the risk of internal bleeding.
- Transient Ischemic Attack (TIA)
- A TIA, or minor stroke, can occur before a major stroke. When a TIA is diagnosed, Plavix or aspirin can be given for three months, followed by either medication.
- Peripheral Artery Disease (PAD)
- PAD is the narrowing of leg arteries, causing pain when patients walk. Patients with PAD are at increased risk for strokes and heart attacks. Either Plavix or Plavix with aspirin lowers the risk of both.
- Aspirin Intolerance
- Aspirin intolerance can occur due to allergy or stomach sensitivity. Some patients’ platelets do not react to aspirin. Those patients are often prescribed Plavix.
Get Treated Online
Did you know? QuickMD can refill Plavix (clopidogrel) online—from the convenience of your home.
