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Erysipelas vs. Cellulitis: Understanding Symptoms, Causes, and Treatments

Erysipelas and cellulitis, although similar in appearance, are serious conditions that require prompt attention. Erysipelas typically affects the outer layers of the skin, while cellulitis can penetrate deeper, potentially spreading throughout the skin. Erysipelas is primarily caused by Streptococcus bacteria, but Staphylococcus can also be a culprit. On the other hand, cellulitis is usually a result of Staphylococcu infection.

Erysipelas vs. Cellulitis: What’s the Difference?

Both conditions often affect the feet and lower legs. Erysipelas, despite its superficial nature, can be quite serious. It causes very well-defined, shiny, reddened areas of skin that are usually painful, along with fever and a general feeling of unwellness. Blisters can form in severe cases. On the other hand, cellulitis causes darker red, less well-defined, painful, swollen skin. Fever and a general feeling of unwellness are less common.

Both erysipelas and cellulitis are bacterial infections that can occur when the skin is compromised, such as through insect bites, scratches, or fungal infections. If left untreated, these infections can escalate, leading to serious complications. Sepsis, a bloodstream infection, or osteomyelitis, an infection of the underlying bone, can develop, underscoring the importance of prompt treatment. 

Early cases may be treated in outpatient settings:

  • Keflex (cephalexin): It can be taken by mouth for 7 to 10 days at a dosage of 1 gram twice daily.
  • Augmentin (amoxicillin/clavulanic acid): Two tablets twice a day can be taken for 7 to 10 days.
  • Clindamycin
  • Bactrim

Remember that even if an effective antibiotic is started, the affected area can still increase by as much as 50% in size. If no improvement is seen within three days, or the patient becomes significantly worse, with high fevers, patients may be admitted to hospitals for IV antibiotic treatment.

Treat Erysipelas and Cellulitis With QuickMD

Did you know? QuickMD offers a convenient solution for treating erysipelas or cellulitis. You can receive treatment in the comfort of your own home and even get a prescription for antibiotics for cellulitis online.

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