Opioid withdrawal is one of the most challenging parts of overcoming addiction, especially if you’re cutting opioids cold turkey. Many often describe the experience as both physically and emotionally intense, with symptoms that can last for days—or even weeks. However, understanding the opioid withdrawal timeline, what happens at each stage, and how to improve your chances of recovery can make the process more manageable.
In this article, we’ll break down how long opioid withdrawal lasts, what to expect during each phase and strategies to make withdrawal safer and more successful.
What Is Opioid Withdrawal?
Opioids, such as oxycodone, heroin, or fentanyl, bind to receptors in the brain, creating feelings of pain relief and euphoria. Over time, the body becomes dependent on these substances, and suddenly stopping can throw it into a state of imbalance. Withdrawal symptoms occur as your brain and body try to readjust to functioning without opioids.
While withdrawal is not typically life-threatening, going cold turkey can feel overwhelming due to the severity of symptoms. That’s why it’s essential to be prepared for what’s ahead and consider ways to improve your chances of successfully navigating this process.
How Long Does Opioid Withdrawal Last?
The duration of opioid withdrawal depends on factors like the type of opioid you were using, how long you were taking it, and your individual biology. However, the general timeline for opioid withdrawal follows these stages:
1. Early Withdrawal Symptoms (6–24 Hours After Last Dose)
The first stage begins within 6–24 hours of stopping opioids, depending on whether you were using short-acting opioids (like heroin) or long-acting opioids (like methadone).
Common Early Symptoms:
- Anxiety or restlessness.
- Muscle aches and joint pain.
- Runny nose and excessive yawning.
- Sweating and chills.
- Insomnia or trouble sleeping.
These symptoms occur as your brain adjusts to the absence of opioids, which had previously suppressed your body’s pain and stress responses.
2. Peak Withdrawal Symptoms (24–72 Hours After Last Dose)
The second stage is often the most intense. Symptoms peak within 2–3 days of stopping opioids and may feel unbearable without proper support.
Common Peak Symptoms:
- Nausea, vomiting, and diarrhea.
- Severe muscle and abdominal cramps.
- Dilated pupils and blurred vision.
- Rapid heartbeat and high blood pressure.
- Strong cravings for opioids.
- Emotional symptoms like irritability, anxiety, or depression.
This stage can be physically and emotionally exhausting, but it’s also the most critical period for staying committed to recovery.
3. Late Withdrawal Symptoms (4–10 Days After Last Dose)
As the peak symptoms begin to subside, the body gradually starts to stabilize. However, emotional and psychological symptoms may linger during this period.
Common Late Symptoms:
- Fatigue and general weakness.
- Mood swings or emotional instability.
- Persistent cravings for opioids.
- Trouble concentrating or “brain fog.”
While the physical discomfort may lessen, emotional symptoms can be challenging, particularly for those going cold turkey without medical support.
4. Post-Acute Withdrawal Symptoms (PAWS)
Even after the physical withdrawal symptoms fade, some people experience Post-Acute Withdrawal Syndrome (PAWS), which can last for weeks or months.
Common PAWS Symptoms:
- Anxiety, depression, or feelings of emptiness.
- Sleep disturbances or vivid, unsettling dreams.
- Difficulty managing stress.
- Lingering opioid cravings.
PAWS occurs because the brain’s neurotransmitters are still healing after long-term opioid use. During this time, professional support and healthy coping strategies are essential.
Cutting Cold Turkey: What to Expect
Going cold turkey—stopping opioids suddenly without tapering—can make withdrawal symptoms feel even more intense. Without medical supervision, you may face:
- Severe cravings: Increasing the risk of relapse.
- Dehydration: Caused by vomiting, diarrhea, and sweating.
- Sleep deprivation: Due to insomnia and restlessness.
- Emotional overwhelm: Anxiety and depression are often heightened.
While some people successfully quit cold turkey, it’s important to know that it’s not the safest or most effective way to stop opioids. Tapering under medical supervision or using Medication-Assisted Treatment (MAT) can significantly reduce withdrawal symptoms and improve your chances of long-term recovery.
How to Better Your Chances of Success
If you’re preparing to quit opioids, here are strategies to make withdrawal safer, more manageable, and more likely to succeed:
1. Consider Medication-Assisted Treatment (MAT)
MAT involves FDA-approved medications like Suboxone (buprenorphine/naloxone) or methadone that reduce cravings and withdrawal symptoms. MAT not only makes withdrawal more tolerable but also lowers the risk of relapse.
QuickMD offers same-day access to Suboxone through online telemedicine appointments, so you can begin treatment without leaving home.
2. Stay Hydrated and Nourished
During withdrawal, dehydration is a common risk due to vomiting and diarrhea. Keep plenty of fluids on hand, like water, electrolyte drinks, or herbal teas. Eat small, nutritious meals to support your body’s recovery.
3. Build a Support System
Withdrawal is difficult to face alone. Let trusted friends, family members, or a support group know about your decision to quit opioids so they can offer encouragement and accountability.
4. Focus on Stress Management
Withdrawal can trigger intense anxiety and emotional discomfort. Consider trying techniques like:
- Breathing exercises to calm your nervous system.
- Meditation or yoga to ease mental and physical tension.
- Journaling to express your emotions and track your progress.
5. Seek Professional Support
Quitting opioids cold turkey can be risky, especially if you have a history of heavy use or co-occurring health conditions. A healthcare provider can create a customized plan, monitor your symptoms, and prescribe medications like Suboxone to support your recovery.
You Don’t Have to Do This Alone
Opioid withdrawal is tough, but it’s also the first step toward freedom and recovery. While symptoms may feel overwhelming at times, knowing what to expect and having a plan can make the process safer and more manageable.
At QuickMD, we’re here to help. Our telemedicine services provide quick, discreet access to Medication-Assisted Treatment (MAT) with Suboxone to ease withdrawal symptoms and support your recovery journey. Don’t wait—contact QuickMD today and take the first step toward reclaiming your life.
