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Suboxone and Pregnancy: Effects of Opioids on Pregnancy, Treatment, and Risk Factors

April 11, 2025

11 minutes

Pregnant woman speaking with a nurse about Suboxone treatment during pregnancy for opioid use disorder

What you’ll learn

This guide explains how Suboxone can support a healthy pregnancy while managing opioid use disorder. You’ll learn how it works, what risks and benefits to expect, and how to find safe, compassionate care for both you and your baby.

Finding out you’re pregnant can bring a mix of emotions, especially when you’re also managing opioid dependency. It’s completely normal to worry about how opioids might affect your pregnancy and your baby’s health. Remember, your concern for your baby’s well-being is already a powerful step toward making the best choices for both of you.

If you’re considering or currently taking Suboxone during pregnancy, you probably have questions. Is Suboxone safe during pregnancy? What might the benefits and risks be for both you and your baby? Could it provide a path to stability during this critical time?

In this guide, we’ll walk through what you need to know about Suboxone and pregnancy in clear, straightforward terms. We’ll explore how opioids affect pregnancy, the potential benefits and drawbacks of treatment, and practical considerations to keep in mind. 

With reliable information, you can make confident decisions that support both your recovery journey and your baby’s healthy development because there is absolutely a path forward that can work for both of you.

How Do Opioids Affect Pregnancy and Fetal Development?

Opioids pass through the placenta, meaning they can affect fetal development.

This connection between mother and baby exists with everything you consume during pregnancy. Many expectant mothers notice how their babies respond to certain foods, perhaps becoming more active after mom drinks orange juice or has a sweet treat. Ultrasound technicians sometimes even suggest mom drink a cold beverage or eat something sugary to encourage movement during an anatomy scan.

Opioid exposure has been linked to an increased risk of preterm birth and low birth weight and, in some cases, more serious developmental concerns, which may require additional medical care after delivery. Many have low birth weights, starting life with an immediate disadvantage. 

The placenta (your baby’s lifeline for oxygen and nutrients) can develop serious problems, sometimes even separating from the uterine wall before birth (placental abruption). In the worst cases, this instability increases the risk of miscarriage or stillbirth.

Many babies exposed to opioids in the womb experience Neonatal Abstinence Syndrome (NAS) after birth. This means they may show signs of withdrawal, such as fussiness, difficulty feeding, or trouble sleeping. Fortunately, hospitals have protocols in place to manage these symptoms, ensuring that babies receive the care and comfort they need.

The cycle of opioid use and withdrawal is particularly harmful. Each time you experience withdrawal, stress hormones flood your system and reduce blood flow to the placenta. Your baby receives less oxygen and fewer nutrients, exactly when they need them most for healthy development. 

Fortunately, there are safer alternatives to this dangerous cycle, namely Suboxone, a mixture of buprenorphine and naloxone. But what is it, and how can it help with pregnancy and opioid use disorder?

What is Suboxone and How Does it Help During Pregnancy?

Suboxone combines two medications that work together to help manage opioid dependency: buprenorphine reduces cravings and withdrawal symptoms, while naloxone prevents misuse.

Buprenorphine attaches to the same brain receptors as other opioids but only partially activates them. This clever partial activation means you avoid the extreme highs of drugs like heroin while also sidestepping those brutal withdrawal symptoms that make quitting feel impossible.

Naloxone acts as the built-in safety feature. It remains dormant when you take Suboxone as prescribed, but jumps into action if someone tries to inject it, blocking the high and preventing misuse.

The real value of Suboxone during pregnancy is stability. Instead of your body (and your baby) riding a constant roller coaster of highs and withdrawals, Suboxone maintains steady medication levels. This consistency is crucial for your developing baby, who depends on reliable blood flow and nutrient delivery through the placenta.

A 2023 review by Prince, Daley, and Ayers confirms what doctors have been seeing for years: pregnant women who receive medication-assisted treatment show significantly better outcomes than those using street opioids.

Suboxone and Pregnancy: Jessie’s Story

“When I found out I was pregnant while managing opioid use disorder, I felt overwhelmed,” says Jessie, who began Suboxone treatment during her first trimester. “Within days of starting treatment, I felt a sense of relief knowing I could focus on my health and my baby’s well-being.” 

By her second trimester, Jessie was attending all prenatal appointments and rebuilding relationships. “Seeing my baby developing normally changed everything. The stability from Suboxone helped me prepare for motherhood instead of worrying about substances.”

This stability is what makes Suboxone valuable during pregnancy. The medication maintains consistent levels in your system, eliminating the harmful cycle of intoxication and withdrawal that stresses both your body and your developing baby.

Jessie’s experience highlights some of the benefits of Suboxone during pregnancy, but it’s important to understand both the potential advantages and risks when making treatment decisions.

Pros and Cons of Using Suboxone for Opioid Addiction During Pregnancy

Let’s be real about what Suboxone offers during pregnancy and where challenges might exist. Because no medical decision is ever one-size-fits-all, especially during pregnancy.

Potential Benefits of Suboxone

Suboxone significantly reduces the risk of relapse. Anyone who’s struggled with addiction knows that cravings can be overwhelming. Suboxone helps quiet those cravings, making recovery possible.

The steady medication levels Suboxone provides eliminate the extreme highs and lows that come with illicit opioid use. This creates a much more stable environment for fetal development.

People receiving stable Suboxone treatment are more likely to receive consistent prenatal care, and that means both mom and baby receive better care throughout pregnancy.

Unlike street drugs (where you can never be sure what you’re getting), Suboxone’s composition is regulated and consistent. What you see is what you get: no dangerous additives or contaminants. 

The research backs this up: studies consistently show improved birth weights and reduced premature births compared to untreated opioid use. In fact, babies born to mothers on medication-assisted treatment had significantly shorter hospital stays than those born to mothers with untreated opioid use disorder.

Potential Risks of Suboxone

Babies exposed to Suboxone during pregnancy may still experience some withdrawal symptoms after birth. However, NAS from Suboxone is typically less severe than with full opioids like heroin or fentanyl.

The research on long-term outcomes is growing but still incomplete. Scientists are working to understand if there are any subtle developmental effects that might appear as children grow. 

Suboxone may interact with other medications sometimes prescribed during pregnancy. This is why coordination between your obstetrician and addiction specialist is crucial.

Pregnancy comes with no shortage of unsolicited advice. From how you eat and move to your birth plan, everyone seems to have an opinion. When you add the stigma surrounding opioid use disorder and medication-assisted treatment, it can feel overwhelming. The judgment, whether from strangers, loved ones, or even healthcare providers, can add to the already long list of physical and emotional challenges that come with pregnancy.

This social pressure can create additional stress during an already challenging time.

Breastfeeding considerations require some additional thought and monitoring, too. Small amounts of buprenorphine do pass into breast milk, though research suggests the benefits of breastfeeding typically outweigh any concerns.

Important Risk Factors and Precautions for Pregnant Patients on Suboxone

Suboxone treatment during pregnancy requires expert supervision, not guesswork.

Never adjust your Suboxone dosage on your own. Changes should happen only under medical guidance. Small changes can have big effects and expertise matters.

Ideally, your care team should include both addiction specialists and obstetric providers working together. They bring different expertise to the table, creating a more comprehensive approach to your care.

Regular monitoring allows for dosage adjustments as your pregnancy progresses. Your body changes dramatically during pregnancy: your metabolism speeds up, blood volume increases, and hormone levels shift. These are all risk factors that can affect how medications work.

As you approach your third trimester, some providers may recommend dose adjustments or split dosing. Your body processes medications differently in late pregnancy, and these adjustments help maintain stable levels.

Liver Conditions and Suboxone Treatment

Using other substances alongside Suboxone increases risks. Mixing substances is unpredictable and potentially dangerous.

Existing medical conditions like liver disease affect how your body processes Suboxone, too. Remember, the liver is your body’s main processing plant for medications, so liver problems can change how Suboxone works.

Mental Health and Suboxone

Mental health conditions often coexist with substance use disorders, too. Depression, anxiety, and trauma require their own treatment approaches that work alongside your Suboxone plan.

Previous Pregnancy Complications

Any previous pregnancy complications might influence treatment decisions moving forward. Your medical history provides important clues about potential risks and benefits.

Planning ahead for delivery makes a big difference. Your delivery team needs to know about your Suboxone treatment to provide appropriate care for both you and your baby.

Will Your Baby Experience Withdrawal Symptoms From Suboxone?

After birth, your baby will be monitored for signs of withdrawal. This doesn’t mean your baby will definitely experience severe symptoms (many don’t), but watchful care is a must for addressing any unpleasant symptoms.

Follow-Up Care

Your pediatrician might recommend specialized follow-up care in the early months of your baby’s life. Consider this like extra insurance; most likely everything will be fine, but regular check-ins help catch any concerns early.

Postpartum Suboxone Treatment: Adjusting to Motherhood and Recovery

And don’t forget about your own needs after delivery. Between midnight feedings, hormone shifts, and the demands of caring for a newborn, the postpartum period brings new challenges to recovery. Your treatment plan may need adjustments to support you through this transition.

Is Methadone Safe During Pregnancy?

Methadone has been around the block a few times. It’s one of the longest-studied medications for opioid use disorder during pregnancy, with research dating back to the 1970s. While effective, it typically requires daily visits to specialized clinics, which can be challenging for pregnant women juggling doctor appointments, work, and family responsibilities.

For some women, especially those with severe opioid dependency, methadone provides better craving control. It remains an excellent option for women who don’t respond well to buprenorphine or who are already stable on methadone treatment.

How Does Buprenorphine Compare to Methadone for Pregnancy Safety?

Recent research offers important insights about pregnancy outcomes. A comprehensive study analyzing 13,360 Medicaid pregnancies (2000-2018) found that buprenorphine was associated with lower risks of birth defects compared to methadone when taken during the first trimester.

The study showed babies exposed to buprenorphine had:

  • Fewer heart defects
  • Lower rates of oral clefts (like cleft lip and palate)
  • Reduced incidence of clubfoot
  • Fewer brain, urinary, and limb defects

One exception was noted: babies exposed to buprenorphine had a slightly higher risk of pyloric stenosis, a stomach condition that can make it difficult for babies to eat.

But despite these differences, medical experts emphasize that both medications are much safer than untreated opioid use disorder.

How Does Subutex Compare to Suboxone During Pregnancy?

Subutex and other buprenorphine-only products give you the same benefits as Suboxone but without the naloxone component.

Some providers may prefer these during pregnancy simply because they contain one less ingredient, though studies haven’t found many differences in pregnancy outcomes between the two.

If you’re doing well on Suboxone, there’s likely no need to switch. But if you experience side effects that might be related to the naloxone, your provider might suggest trying a buprenorphine-only alternative.

What Complementary Treatments Work with Medication for Pregnant Women?

Medication is just one part of your pregnancy recovery from opioids. These complementary approaches can make a real difference:

Behavioral Therapy

Behavioral therapy helps you develop healthier thought patterns and coping skills that support your recovery. It gives you practical tools for those moments when cravings hit, like TikTok notifications; constant and hard to ignore. You’ll work on strategies that actually help in real life.

Peer Support Groups

Connection matters tremendously during pregnancy. Peer support groups introduce you to others walking a similar path who truly understand your experience and can share practical wisdom.

No need to explain why you’re on medication or worry about judgment, just practical wisdom from those in the same boat.

A Note of Caution About “Detoxing” During Pregnancy

Despite what well-meaning friends or family might suggest about “just getting clean,” medical experts strongly recommend against attempting complete detoxification during pregnancy. 

The risks, (including relapse, withdrawal-induced stress on your baby, and potential complications), simply outweigh any perceived benefits.

Medication-assisted treatment offers the safest path forward for both you and your baby. With proper treatment and support, you can look forward to a healthy pregnancy and a bright future for your growing family.

QuickMD offers specialized telehealth services that make accessing proper care simpler and more convenient than ever before.

How QuickMD Can Help You With Suboxone Treatment During Pregnancy

Look, finding doctors who understand both pregnancy and addiction isn’t easy. That’s where QuickMD comes in: we’ve got specialists who actually get what you’re going through.

Care From Your Couch

Pregnancy is already a lot to manage: morning sickness, prenatal visits, and the daily demands of life. The last thing you need is the added stress of making it to yet another appointment. QuickMD lets you connect with addiction specialists from home.

  • No more stressing about getting to appointments when you’re already exhausted
  • Privately accessible care from home, making it easier to focus on your health
  • Quick appointments when you need them, because pregnancy doesn’t wait for scheduled office hours

Between ultrasounds, OB visits, and maybe working or caring for other kids, the last thing you need is another complicated schedule to manage.

With clear pricing, you can focus on your health instead of stressing about surprise bills. No transportation costs, no childcare needed for appointments, just straightforward care when you need it. With the right support, you’ve got this!

Suboxone and Pregnancy: Your Path to a Healthier Pregnancy Starts Today

With medication-assisted treatment like Suboxone, comprehensive support, and proper medical care, you can create stability for both yourself and your baby.

Remember that seeking help isn’t a sign of weakness; it’s a powerful commitment to your child’s future. Every day you maintain treatment is a gift to your developing baby.

Ready for recovery?

If you’re ready to start your journey with compassionate, judgment-free care, QuickMD is here to support you. You don’t have to do this alone. We’re here to help every step of the way.

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Frequently Asked Questions

Will my baby have withdrawal symptoms after birth?

Some babies experience Neonatal Abstinence Syndrome (NAS), but symptoms are typically milder than with illicit opioids. Hospital staff will monitor your baby and manage any discomfort. Treatable withdrawal is safer than untreated opioid use during pregnancy.

Will healthcare providers judge me for using Suboxone during pregnancy?

More providers now recognize medication-assisted treatment as standard care for pregnant women with opioid dependency. If you encounter judgment, remember you’re following medical best practices. QuickMD offers providers trained in addiction medicine who understand the importance of medication during pregnancy.

When should I tell my doctor I’m taking Suboxone?

Immediately. Being upfront allows proper coordination between your addiction specialist and prenatal provider. This helps them monitor you and your baby, adjust medication as needed, and prepare for delivery. Your medical information is protected by privacy laws.

Disclaimer

Disclaimer Articles on this website are meant for educational purposes only and are not intended to replace professional medical advice, diagnosis or treatment. Do not delay care because of the content on this site. If you think you are experiencing a medical emergency, please call your doctor immediately or call 911 (if within the United States). This blog and its content are the intellectual property of QuickMD LLC and may not be copied or used without permission.

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